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La codeina è un analgesico (allevia il dolore) dotato anche di effetto contro la tosse. Agisce modificando il modo in cui il cervello e il sistema nervoso rispondono al dolore e riducendo l'attività delle aree cerebrali che controllano la tosse.
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To prevent the indicators from the common chilly, the flu, asthma, or other respiratory Conditions (such sinusitis or bronchitis), a combination medication is used. Colds are certainly not getting cured by cough and cold medications. Occasionally a cold or flu can take care of a cough with no need for medication.
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Everyday living-threatening respiratory melancholy is a lot more more likely to take place in elderly, cachectic, or debilitated people as they can check here have altered pharmacokinetics or altered clearance in comparison with click here more youthful, healthier sufferers
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Daily life-threatening respiratory depression and death have happened in little ones who obtained codeine; codeine is topic to variability in metabolism based mostly upon CYP2D6 genotype; primarily based on write-up-advertising and marketing reviews, small children < twelve yrs seem like far more liable to respiratory depressant consequences of codeine, notably if you'll find possibility aspects for respiratory melancholy; conditions of Demise have already been claimed within the publish-operative interval next tonsillectomy and/or adenoidectomy, and plenty of of the kids experienced proof of remaining extremely-fast metabolizers of codeine
Use is contraindicated in individuals acquiring monoamine oxidase inhibitors (MAOIs) or within just fourteen days of stopping this kind of therapy; read more MAOIs might potentiate effects of codeine’s Lively metabolite, together with respiratory despair, coma, and confusion